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The medical ethics committee of the Hospital Network Antwerp (ZNA, approval numbers 2805 and 2806) granted the ethical approval and the study was compliant with the World Medical Association Declaration of Helsinki on Ethical Principles for Medical Research Involving Human Subjects

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24 : 94149423 Loeffler M, Daugas E, Susin SA, Zamzami N, Metivier D, Nieminen AL, Brothers G, Penninger JM and Kroemer G (2001) Dominant cell death induction by extramitochondrially targeted apoptosis-inducing factor

Past records have indicated that milk thistle has been for used more than 2,000 years