doi: 10.1016/j.genhosppsych.2023.08.009 28 MazzaMGPalladiniMDe LorenzoRMagnaghiCPolettiSFurlanRet al
Phase 2 clinical trials for retatrutide used a gradual titration protocol, starting at 2 mg and increasing every four weeks up to the target dose
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It also helps stabilize blood sugar levels, which can reduce energy crashes and emotional eating
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Neither study showed a significant increase in amylase (7% for both studies) or lipase (28% in the LEADER trial and 31% in the SCALE trial) values after starting liraglutide compared with placebo, and the positive predictive values of amylase and lipase for pancreatitis were less than 1%