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However, off-label prescribing is legal and common in medicine, and it requires clinical rationale, informed consent, and monitoring

Access to TriNetX data is available to qualified researchers through TriNetX (TriNetX, LLC) subject to a data use agreement and applicable institutional requirements

Some protocols involve longer continuous use for 6-12 months with ongoing monitoring

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Rights and permissions About this article Cite this article Abdel-Aziz, M.A., Ahmed, H.M.S., El-Nekeety, A.A

doi: 10.1038/s41586-020-2634-9 228 BuscarinuMCCerasoliBAnnibaliVPolicanoCLionettoLCapiMet al