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Multi-dose vials usually contain a preservative (such as benzyl alcohol) to prevent microbial growth after the vial is first punctured

doi: 10.1016/j.mehy.2004.03.037

134 A randomized placebo-controlled trial in 120 subjects who described their sleep as unsatisfactory found treatment with 14 mg or 28 mg of a standardized saffron extract, taken one hour before bedtime for 28 days, improved subjective sleep quality and mood scores

Deore MS, Naqvi SK, Kumar S, Flora A

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