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Animal model studies have suggested that GLP-1RAs may cause pancreatitis and exocrine dysplasia, but in the large RCTs and a meta-analysis, GLP-1RAs did not increase the risk of pancreatitis or pancreatic cancer [82,83]

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Because of these uncertainties, several leading medical organizations including the American Diabetes Association and Obesity Medicine Association have recommended against using non-FDA-approved compounded GLP-1s

Their appetite suppression does not kick in as reliably, or they feel like they are not getting the same effect from the same dose

Anyone who experiences severe symptoms should stop taking the medication,contact their healthcare provider right away or seek urgent care Wegovy vs