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All children and adults cycle through stages of deep sleep, also known as non-rapid eye movement (non-REM), and light sleep, also known as REM

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In the UK, cyanocobalamin is commonly used for oral supplementation due to its stability and effectiveness, whilst hydroxocobalamin injections are the preferred treatment for confirmed deficiency, particularly in pernicious anaemia or malabsorption conditions

The migratory abilities of these cells, and their propensity to seed different neural niches, can give rise to the genomic heterogeneity as seen in BM patients [70]

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Fragmented, unrestful sleep