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Caution applies for individuals with cardiovascular conditions, though topical application minimizes systemic exposure

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PMID: 17147644 Alven, S., Peter, S., Mbese, Z., & Aderibigbe, B

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used 0.1 mg/kg subcutaneously in scopolamine-induced amnesia models, while traumatic brain injury research has employed higher doses up to 5.0 mg/kg