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Lenvatinib-activated Ndufa4l2/Il33/Padi4 pathway induces neutrophil extracellular traps that inhibit cuproptosis in hepatocellular carcinoma

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Researchers observed marked differences in the expression levels of GPER in different types of thyroid tissues, particularly in comparisons between benign and malignant thyroid tumors, with relatively low GPER expression levels in malignant tumors, further emphasizing the potential role of GPER in thyroid diseases [206]

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For instance, although administering T-2 at a sublethal concentration resulted in lower numbers of B cells (CD19 + ), opposite effects were noted when Se was injected simultaneously or 24 h prior to the toxin