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Mechanistically, GLP1RAs improve cardiac function by enhancing contractility and reducing myocardial injury 14,15,16 , exert vasodilatory and endothelial-protective effects, and display anti-inflammatory and anti-fibrotic actions that may limit adverse remodeling in heart failure (HF) 17
Kenyon, E., Westerhuis, J
The PT-141 peptide, also known as bremelanotide, is sold as a prescription medication under the brand name Vyleesi
Ulcerative Colitis Study Group
Gut microbe-derived metabolite trimethylamine N-oxide accelerates fibroblast-myofibroblast differentiation and induces cardiac fibrosis
Research literature characterised honestly qualified throughout ("research models," "in vitro/in vivo/clinical" distinction made explicit), no overstatement
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