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These include limited long-term safety data across diverse populations, insufficient understanding of mechanisms in neuropsychiatric and oncologic contexts, and suboptimal communication between clinicians and patients

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An increased Ca/ Mg might also contribute [29,30]

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The timeline for seeing results with GLP-1 receptor agonists varies from person to person and depends on factors such as starting weight, adherence to treatment, diet, exercise, and overall health

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Third, both the rates of, and factors associated with, treatment discontinuation were similar for GLP-1 receptor agonists and SGLT2 inhibitors, indicating that patient-specific factors, rather than drug-specific factors (such as side-effects), are driving treatment discontinuation

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