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1,2 Type I (immediate) hypersensitivity reactions occur when IgE binds and cross-links to a specific antigenic determinant

However, only R -LA is conjugated to conserved lysine residues in an amide linkage (forming a lipoamide), thus making this isoform essential as a cofactor in biological systems

The compound belongs to a class known as NNMT inhibitors

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Several representative genes associated with basal resistance were identified including a GST gene (EBR-52) closely related to the auxin-inducible tobacco gene par-B