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GIP receptor activation enhances insulin secretion, improves fat metabolism, and may contribute to central nervous system effects on appetite that go beyond what GLP-1 alone can achieve

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The significance of this paper is not only to compare the three routes of administration but also to evaluate them and determine which route is the best to administrate the drug

Vanhove, K., Derveaux, E., Graulus, G.-J., Mesotten, L., Thomeer, M., Noben, J.-P