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TABLE 4 Mechanism of action and level of observed therapeutic benefits of semi-synthetic and synthetic AT mentioned in this review

PloS One 2010

Maternal obesity during lactation may protect offspring from high fat diet-induced metabolic dysfunction

Additionally, in an in vitro allergic rhinitis airway epithelial model system of human nasal epithelial cells, IL-13 stimulation in the presence of formononetin treatment (10 M) suppressed upregulated proinflammatory cytokines and mucus formation, potentially though the sirtuin (SIRT1)/Nuclear factor erythroid 2- related factor 2 (NRF2) signaling pathway [119]

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7 Copper-tripeptide complexes stimulate dermal papilla cell proliferation and shift these cells toward survival by raising the Bcl-2/Bax ratio and reducing apoptosis markers