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Nutrition Needs of Mammalian Cells in Tissue Culture

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4.9 Alpha-Lipoic Acid In its reduced dihydrolipoate form, alpha-lipoic acid (ALA) reacts with ROS and reactive nitrogen species and protects cell membranes by interfering with the vitamin C and E pathways [124]

Because reactive oxygen species (ROS) play key regulatory roles in multiple redox-sensitive signaling cascades, maintaining their concentrations within a physiological range is essential for cellular homeostasis

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