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This type of indirect comparison has significant limitations: Different Patient Populations: The compared studies may have enrolled patients with different baseline characteristics, comorbidities, or weight loss history Different Time Periods: Studies conducted at different times may reflect different clinical practices, patient expectations, or medication formulations Different Outcome Measures: How weight loss was measured, when it was measured, and how dropouts were handled may differ between studies Selection Bias: Patients who complete a 68-week telehealth program may differ systematically from those who complete an in-person clinical trial The lack of a head-to-head comparison means the 46% figure should be interpreted as a retrospective analysis rather than evidence from a controlled trial

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When you have babies and toddlers, its routineyoure scheduling these frequently, said Dr

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I was also happy to see that this study also included an active comparator arm