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There are also emerging concerns about the quality of weight loss

Souza MDAD, Nassini R, Geppetti P, et al

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Although skeletal muscle creatine synthesis will be impaired in individuals with GATM and GAMT mutations, impaired muscle function is not the major symptom in creatine deficiency syndrome patients

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Access to weight loss drugs is a major issue and most private insurance companies consider cover for weight loss treatment as an exclusion