The fitted models were further refined by rounds of manual model building in COOT 54 and real-space refinement, as implemented in the PHENIX software package 55
Aging Cell, 20(4), e13350
They are abundant in plant-based foods, including fruits, vegetables, cereals, and beverages, and comprise a complex group of over 8000 known compounds ( Based on the number of phenolic rings and structural linkages, they are commonly categorized into five main classes: tannins, lignans, phenolic acids, flavonoids, and stilbenes ( This review highlights the major classes of polyphenols, evaluated as secondary metabolites, along with methods used for their extraction and characterization
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