PG gene is expressed in pancreatic -cells, intestinal L cells, and some nerve cells, and through tissue-specific translation modification, different end products are finally formed
The genetic variants used as instruments model a modest, lifelong modulation of receptor pathways
The most common side effects are mild nausea, decreased appetite, constipation, or bloating usually temporary as your body adjusts
At the highest dose (12mg), approximately 20.9% of participants reported this side effect
Diabetes Obes Metab (2022) 24:23946
Not necessarily dangerous, but it needs medical oversight and close glucose monitoring