About practical factors: Do you strongly prefer pills over injections, or vice versa
The glucagon component is believed to increase energy expenditure, essentially helping the body burn more calories
When you activate GLP-1 receptors in the stomach lining and chemoreceptor trigger zone (a nausea-control region in the brain), your stomach empties more slowly, signaling fullness faster
How should you take it
Arch Biochem Biophys 221(2):526533 Zhu JJ, Xu YQ, He JH, Yu HP, Huang CJ, Gao JM, Dong QX, Xuan YX, Li CQ (2014) Human cardiotoxic drugs delivered by soaking and microinjection induce cardiovascular toxicity in zebrafish
Gastrointestinal adverse events Very common (10% or more): Diarrhea (35%), abdominal pain (21%), vomiting (21%), nausea (12%) Common (1% to 10%): Constipation, dyspepsia, gastrointestinal disorder, melena Very rare (less than 0.01%): Abdominal cramps [Ref] Nervous system Very common (10% or more): Headache (37%), dizziness (18%), paresthesia (12%) Common (1% to 10%): Hypertonia, vertigo, taste perversion Frequency not reported : Seizures (with or without pre-existing seizure activity), increase in seizure frequency and/or severity [Ref] Metabolic Very common (10% or more): Hypercalcemia (15%), hypervolemia (12%) Common (1% to 10%): Anorexia, hyperkalemia [Ref] There are reports from clinical trials of significant hypertriglyceridemia associated with high doses of levocarnitine (3 g/day) given to uremic dialysis patients
