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Semaglutides benefits for shedding pounds were discovered accidentally

The medication occupies GLP-1 receptors to work in the following ways: Semaglutide acts on the hunger control center (lateral hypothalamus) of the brain to promote a feeling of fullness, which suppresses an urge to eat and reduces the intensity of hunger cravings

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Yes, Contrave can cause an increase in blood pressure and heart rate, which is why it should not be used by people with uncontrolled hypertension