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However, the MHRA has issued safety warnings about the risk of diabetic ketoacidosis (DKA) with SGLT2 inhibitors, particularly during periods of reduced caloric intake or illness

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The exact mechanism of topiramate is not well understood, but it augments weight loss induced by phentermine through suspected modulation of GABA receptors, carbonic anhydrase inhibition, and glutamate antagonism [36]

"" indicates an increase in the abundance of the corresponding intestinal microbiota taxa, and "" indicates a decrease in the abundance of the corresponding intestinal microbiota taxa