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It indicates mild inflammation around the follicle and is commonly seen in androgenetic alopecia

So it may be that the liver has to work extra hard to detoxify the body when its low 0on B12, even when there's no liver damage

Role for malic enzyme, pyruvate carboxylation, and mitochondrial malate import in glucose-stimulated insulin secretion

It has been widely used in preclinical therapy for tumors, intestinal diseases, and anemia via oral administration 20,21,22

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