drugs that target glp 1 GLP-1-based therapies for diabetes, obesity and beyond Indications for GLP-1/GIP RA Summary

186 However, T cells have a mechanism to combat arginine deficiency: when confronted with arginine deficiency caused by Arg1-expressing myeloid cells, T cells increase arginine biosynthesis by up-regulating ASS1 expression

Concentrations were calculated based on relative spiked IS amount, with data normalized across runs using the quality control sample that was run along with each batch

JAKSTAT (2014) 3(1):e28087.10.4161/jkst.28087 139 RamPAWaxmanDJ

Wang Y, Yu R, Wu L, Yang G

PLoS ONE 9 , e90284 (2014)

We entered overlapping DEGs as a query signature in the CMap database and the top ten small-molecule drugs are listed in Table 1