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This is Part 2 of our leave benefits series
In lung and colon tumors, the inhibition of glutamine utilization led to an increase in PD-L1 expression by reducing GSH levels [170]
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Regardless, the possibility that down-regulation of other redox-dependent genes or processes upon p53 stabilization, or in response to other conditions leading to cell cycle arrest, can promote GSH accumulation and inhibition of ferroptosis cannot be excluded
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Methods Study population We conducted a multicenter retrospective observational study using TriNetX (TriNetX, LLC, Cambridge, Massachusetts, USA), a global healthcare data and analytics platform
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