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The overexpression of GSTs in cancer cells offers unique opportunities for prodrug therapy 108

But the most striking finding was the effect on relapse frequency

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Consistency with dosing during this establishment phase helps build the foundation for subsequent improvement

Rapamycin-induced autophagy ameliorates GSH depletion-induced premature cell senescence It was shown that autophagy activation especially in the presence of an increasing autophagic flux inhibits the senescence of RPE cells 35,36,37,38,39

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