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Nelson, R.E., Fessler, L.I., Takagi, Y., Blumberg, B., Keene, E.R., Olson, P.F., Parker, C.G
SFAs and ceramide) exhibit detrimental effects on mitochondrial function
139 PompeianoM.CirelliC.Ronca-TestoniS.TononiG
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The 28-week, phase three, Evaluate Efficacy and Safety of Exenatide Once Weekly and Dapagliflozin Versus Exenatide and Dapagliflozin Matching Placebo (DURATION-8) trial demonstrated that dual therapy with dapagliflozin and exenatide had additive effects on lowering weight and blood pressure, though with a less than additive effect on HbA1c [102]