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In streptozotocin-induced diabetic mice, Ex-4 has been observed to regulate the cell cycle via the PKA/activating transcription factor 1 (ATF-1)/-catenin/cyclin D1 pathway, thereby enhancing proliferation of -cell [34]

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As the first step, the eryptotic rate, as well as conventional and unconventional systemic inflammatory indices (C-reactive protein (CRP), IL-6, and IL-1), was compared in 31 PD patients with diagnosis of acute peritonitis and 34 PD patients without any history of systemic inflammation and peritonitis in the last 3 months, as control group