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NAD+ is a large molecule that the body often finds difficult to transport directly into the cells from the digestive tract
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Patients on chronic corticosteroids (asthma, autoimmune diseases) have impaired tissue healing, a well-known clinical problem
the definition of this profile showed a good level of homogeneity (mean inter-item Spearman 0.25) [41] and has been extensively described previously as belonging to the immuno-metabolic depression (IMD) domain, based on previous findings on individual symptoms with immuno-metabolic dysregulation [2]
