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It's sterile water containing 0.9% benzyl alcohol, which acts as a preservative to prevent bacterial growth after the vial has been opened multiple times

The most common pathway involves dehydration resulting from gastrointestinal side effects, particularly vomiting and diarrhea, which can lead to fluid loss and compensatory thirst

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The biological shift starts around 35 with declining growth hormone, not when menopause arrives

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Nitroglycerin and the isosorbides are converted to nitric oxide through the action of mitochondrial aldehyde dehydrogenase (encoded by the ALDH2 gene)