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A pathophysiological mechanism underlying pregnancy-associated thyroid disorders as HT and PPT involves a complex interplay of genetic predisposition, epigenetic modifications, immune dysregulation, and chronic inflammation, all of which contribute to oxidative stress and progressive thyroid dysfunction [19]

Nevertheless, other randomized clinical trials failed to demonstrate any beneficial effect of selenium supplementation in GD (81, 82) or in HT [79, 80]

8c, f, Supplementary Figs

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Vitamin B6 Depending on the severity of a vitamin B6 deficiency, you may experience symptoms like [6]: Rashes More frequent infections Cheilitis (inflamed lips) Glossitis (inflamed tongue) Anemia Depression According to a recent study in the journal Nutrients, there is also growing evidence that a lack of vitamin B6 can increase the chances of developing some forms of cancer [4]