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At 0.1, 1, 10, 50, and 100 mM, 6-shogaol suppressed the production of IL-6 and TNF- in human mast cells (HMC-1)

This is relevant, as platelets are the first cells that arrive at a site of injury to release various factors that initiate the repair process

CrossRef UV Irradiation Increases Appetite and Prevents Body Weight Gain through the Upregulation of Norepinephrine in Mice Qing-Ling Quan, Eun Ju Kim, Sungsoo Kim, Yeon Kyung Kim, Min Hwa Chung, Yu-Dan Tian, Chang-Yup Shin, Dong Hun Lee, Jin Ho Chung Journal of Investigative Dermatology.2024

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As leses plantares so caracteristicamente dolorosas com a deambulao, provavelmente pela formao de bolhas sob as reas hiperceratticas