With high energy output from mitochondria comes higher free radical and ROS production and greater susceptibility to oxidative stresswhich is where glutathione comes in again.* The sirtuin SIRT3a longevity-related protein that requires NAD+ for proper functioningis also involved here, helping to maintain hearing during aging by promoting glutathione-mediated antioxidant defense systems
Quality vs Quantity A supplement is only as good as its bioavailability, which is its ability to be absorbed and used by the body
These are not FDA approved medications
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N-Acetylcysteine (NAC) Supplements: NAC is a precursor to cysteine and has been shown to support glutathione synthesis
Gierach M, Gierach J, Skowroska A, Rutkowska E, Spychalska M, Pujanek M, et al