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The episode emphasizes the critical role of circadian rhythms, influenced by factors like light exposure, temperature regulation, and eating schedules

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Long-term IGF-1 elevation has theoretical implications for cell growth, which is one reason cancer history is treated as an exclusion

The Problem the Scale Cannot See Multiple international studies on Semaglutide and related GLP-1 drugs have shown that a significant proportion of total weight lost can come from lean muscle mass, not just body fat

Survodutide (BI 456906) is a GLP-1R/GCGR dual agonist developed by Boehringer Ingelheim, with outcomes of a phase 2 trial in MASLD and a phase 1 trial in cirrhosis published almost simultaneously with tirzepatide