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The mutation analyses could be interpreted as heterozygous, homozygous or compound heterozygous without additional PCR runs since the wild type probes have been incorporated into the test kit for comparison

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Moreover, the abundance of bacteria carrying bile salt hydrolase and bile acid inducible enzyme in the gut microbiota of IBD patients, such as Firmicutes , Ruminococcaceae , Lachnospiraceae , and Eubacterium , is reduced

The signaling pathway works through interleukin-6 (IL-6) induction