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A 2023 review in Archives of Physiology and Biochemistry found that berberine stimulates GLP-1 secretion by modulating gut microbiota and influencing insulin signaling pathways

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J Cachexia Sarcopenia Muscle 2(3):153161 Garcia JM, Boccia RV, Graham CD, Yan Y, Duus EM, Allen S et al (2015) Anamorelin for patients with cancer cachexia: an integrated analysis of two phase 2, randomised, placebo-controlled, double-blind trials

Here is what I consider before any peptide conversation with a patient: Theoretical Risks Cancer promotion: Because BPC-157 promotes angiogenesis (new blood vessel formation), there is a legitimate theoretical concern that it could accelerate growth of pre-existing tumors

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