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With the advent of longacting therapies that include glucagonlike peptide1 (GLP1) receptor agonist activity (e.g., semaglutide and the glucosedependent insulinotropic polypeptide [GIP]/GLP1 receptor dual agonist tirzepatide), greater and more sustained weight loss has become achievable medically
This dual-layered approach of combining GLP-1, GIP, and GCG actions may make Retatrutide more effective in reducing hunger and increasing feelings of fullness, compared to medications like tirzepatide
Hurtado et al
Veronese, N
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