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[7] Recent mechanistic data further support its therapeutic potential

At 2.5mg per week, a 10mg vial with 2ml of water provides exactly four doses

Finally, they reflect pathways likely additional to those involved in the angiogenesis (Vukojevic et al., 2018), recently associated in particular with the increased expression, internalization of VEGFR2, and the activation of the VEGFR2-Akt-eNOS signaling pathway ( Genes Expression as Support ), given the rapid presentation of all of these effects, which occurred before the process of angiogenesis could be initiated (Sikiric et al., 1993

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