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Excessive dosing may cause fluid retention, joint stiffness, or carpal tunnel-like symptoms

The pharmacological landscape of insulin varies, with types like insulin glulisine, aspart, and lispro offering rapid, short-duration control over postprandial glucose surges, while insulin detemir and glargine serve as long-acting insulins, providing consistent basal levels

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Moreover, melatonin may impact amyloid clearance via its impact on insulin-degrading enzyme (IDE), a protease pivotal for catalyzing extracellular and intracellular A degradation [63]