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Based on preclinical (animal and cellular) data only, inhibition of NNMT by 5-Amino-1MQ is theorised to: Raise intracellular NAD+ levels Activate SIRT1 and other sirtuins (proteins linked to metabolic regulation) Reduce fat cell (adipocyte) size and proliferation Improve insulin sensitivity These effects have been demonstrated in mouse models (Neelakantan et al., 2019), but robust human clinical trial data are currently absent
Low potassium levels : This is very rare but can happen when your body starts making more red blood cells after treatment
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Potential Cartilage & Joint Repair Benefits Some researchers propose that AOD-9604 may aid in cartilage regeneration and joint recovery, potentially helping individuals with: Osteoarthritis or cartilage degradation Injury recovery, particularly in athletes Post-exercise inflammation reduction 4