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It has also been observed that patients taking GLP-1 or GLP/GIP medications are at risk of losing lean muscle mass during weight loss, so it is important for patients to maintain adequate sources of protein in their diets

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These studies indicate that GLP-1 modulates the release of several neurotransmitters including serotonin, dopamine, GABA, and glutamate, which may regulate depressive-like behaviors

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