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Systemic anti-inflammatory signaling: TB-500 downregulates inflammatory cytokines across multiple tissue types, including muscle, tendon, cardiac, and neural tissue

The compound is described in the literature as pleiotropic: its downstream effects engage multiple biological systems simultaneously, and its primary binding receptor has not yet been identified

Hope DCD, Hinds CE, Lopes T, Vincent ML, Shrewsbury JV, Yu ATC, et al

But a percentage of those broken chains are now biologically inactive fragments that your body cannot use

Tissue sections were incubated overnight at 4C with the pH2A.X antibody (1:300, #2577

In addition, it appears to modulate various molecular pathways that are involved in inflammation, immune function, and nerve regeneration