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Models explore pulsatile GH-axis dynamics, second-messenger responses, and combinatorial pathway effects in vitro

Various small-molecule inhibitors targeting different stages of NLRP3 activation have been developed and investigated preclinically

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Matching process We used a propensity score matching (PSM) method to compare the new users of GLP-1RAs with new users of SGLT2 inhibitors, metformin and other second- or third-line glucose-lowering drugs

Eligible patients who completed the screening period entered the lead-in treatment period, which included 16 weeks of open-label metformin HCl and 10 mg dapagliflozin treatment

Mass spectrometry, HPLC, and other analytical techniques can quantify intact peptide remaining after storage