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Prolonged exposure to light can also degrade GLP-1 medications, which is why they are supplied in opaque or light-protective packaging

A comprehensive literature search was conducted across multiple electronic databases including PubMed, Cochrane Central Register of Controlled Trials, and Google Scholar

The transmethylation axis: Methionine is the precursor for SAM (S-adenosylmethionine) the universal methyl donor that methylates DNA, histones, RNA, proteins, phospholipids, neurotransmitters, and numerous other metabolites

Dehydroascorbate is reduced to ascorbate by dehydroascorbate reductase (DHAR) at the expense of GSH, yielding oxidized glutathione (GSSG)

More importantly, there are numerous inflammatory signal pathways involved including nuclear factor (NF)-B, NLRP3, or MAPK

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