Pro-inflammatory cytokines can directly inhibit hair follicle stem cells and shorten the anagen phase
WEIGHT GAIN In the UKPDS, sulfonylurea treatment caused a net weight gain of approximately 3 kg, which occurred during the first 3-4 years of treatment and then stabilized (21,34)
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Statistical significance was assessed using one-sided ANOVAs followed by Sidaks and Dunnetts ( c , d ) multiple comparisons adjustments, paired t- tests ( e ), repeated measures two-sided ANOVAs followed by Dunnetts multiple comparisons adjustment ( f ), KruskalWallis tests followed by Dunns multiple comparisons adjustment ( g , h , i (Y3.3)), or Welchs one-way ANOVA followed by Dunnetts T3 multiple comparisons adjustment ( i (Y1.7))
Psychiatry 21, 885893
These bound complexes become water-soluble, which allows the liver to process them for excretion