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Clinical data so far have shown that retatrutide dose-dependently increases heart rate up to 6.7 bpm at 24 weeks and declined thereafter (83) while pulse rate increased with increasing doses of tirzepatide peaking (6.6

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In 2025, biosimilars held approximately 20 percent average market share of the total biologics market in the US, up from less than 5 percent in 2020

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