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Komives presented a comprehensive review discussing the utility of HDX-MS in discovery of IDRs in proteins, monitoring coupled folding and binding, and characterization of protein aggregates and oligomers ( 2.13.2 Ion mobility-mass spectrometry (IM-MS) Ion mobility-mass spectrometry (IM-MS) is an analytical technique that separates ions based on their collision cross-section (CCS, which is a measure of the size and shape of ion that defines its collision rate) in the gas phase

Over the last two decades, even as the overall number of studies published has risen dramatically, the rate of retraction has actually eclipsed the rate of publication

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Ng, M., et al