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In tophus formation, heterogeneous nucleation is the predominant mechanism, whereby MSU crystals preferentially form on pre-existing solid surfaces, or nucleation seeds, rather than spontaneously in a homogeneous solution

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Serum analysis assessed the levels of reduced glutathione (GSH) to determine supplement absorption

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(2016) found that fasting serum TMAO levels correlated positively with carotid intima-media thickness (cIMT) independently of established CVD risk markers such as insulin resistance, fatty liver, and visceral obesity