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Front Pharmacol 15: 1414268

Semaglutide, a GLP-1 receptor agonist approved by the FDA for chronic weight management, does reduce abdominal fatbut not through spot reduction

A typical plan pauses semaglutide before conception attempts and uses other approaches to manage diabetes or weight-related risks

Published in European Neuropsychopharmacology, the study builds on earlier hypotheses that GLP-1 receptor drugs might influence drug-seeking behavior, but semaglutide's long-acting effect created far more powerful results

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