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In Phase 2 clinical trials, the safety profile was broadly consistent with other incretin-based therapies, with gastrointestinal side effects being the most commonly reported

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JAMA Neurol 78(6):678686 Witry M et al (2021) The patients perspective on the burden of idiopathic intracranial hypertension

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NHS England states that tirzepatide prescribing in primary care requires wraparound clinical and behavioural support

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Based on Drug Discovery & Development s Pharma 50 data and Novos own guidance, we estimate that the companys semaglutide franchise could reach roughly $36 billion in 2026, up from about $33 billion in 2025

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Now production cannot keep up with demand for this instant blockbuster peptide drug, also marketed for weightloss as Wegovy, and the similar GLP-1 drug developed by Lilly, tirzepatide (Zepbound or Mounjaro)

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