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Notably, the lipid droplets intheliversofHFD model mice were of varying size, which clearly showed that HFD feeding resulted in hepatic lipid accumulation, exhibiting mixed micro-vesicular to macro-vesicular steatosis

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Mechanistically: BPC157 enhances fibroblast activity, collagen synthesis, and angiogenesis at the injury site, supports the GI lining, and modulates inflammatory cytokines and oxidative stress

10.1042/BST20200270 Summary Keywords GLP-1, immunemetabolic signaling, metabolic disease, neuroendocrine peptides, orphan receptors, peptide therapeutics, polypharmacology Citation Niazi SK (2026) Beyond GLP-1: underexplored peptidereceptor systems as the next frontier in drug discovery

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GLP-1, or glucagon-like peptide-1, is a hormone secreted in the gut that plays a vital role in appetite regulation and glucose metabolism